Here are 50 of the most common questions about Mounjaro (Tirzepatide) along with pharmacist-approved answers:

General Information

1. What is Mounjaro? Mounjaro (tirzepatide) is a once-weekly injectable medication used to treat type 2 diabetes by mimicking two hormones: GLP-1 and GIP, which help regulate blood sugar levels.

2. Is Mounjaro FDA-approved for weight loss? Mounjaro is approved for type 2 diabetes, but studies show it can aid weight loss. It may soon receive FDA approval for obesity management.

3. How does Mounjaro work? Mounjaro stimulates insulin release, suppresses glucagon, slows digestion, and reduces appetite, leading to improved blood sugar control and potential weight loss.

4. How is Mounjaro different from Ozempic? Ozempic (semaglutide) only mimics GLP-1, while Mounjaro mimics both GLP-1 and GIP, potentially leading to greater blood sugar control and weight loss.

5. Is Mounjaro a type of insulin? No, Mounjaro is not insulin. It helps the body use insulin more effectively but does not replace it.

   
   

Usage & Dosage

6. How do you take Mounjaro? Mounjaro is injected subcutaneously (under the skin) once a week in the stomach, thigh, or upper arm.

7. Can I change the day I take Mounjaro? Yes, as long as there are at least 3 days (72 hours) between doses. Do not take two doses within 3 days.

8. What happens if I miss a dose? If it’s within 4 days, take the missed dose as soon as possible. If more than 4 days have passed, skip it and take the next dose on schedule.

9. What are the available doses of Mounjaro? Mounjaro comes in 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg doses. Most patients start at 2.5 mg and gradually increase.

10. How long does Mounjaro take to start working? Some people notice reduced appetite and improved blood sugar within a few days, but full effects take several weeks.

Side Effects & Safety

11. What are the common side effects of Mounjaro? Nausea, vomiting, diarrhea, constipation, decreased appetite, and mild injection site reactions.

12. How can I reduce nausea from Mounjaro? Eat smaller meals, avoid greasy foods, and stay hydrated. Some people find taking the injection before bed helps.

13. Can Mounjaro cause low blood sugar? It usually doesn’t unless combined with insulin or sulfonylureas (e.g., glipizide). Symptoms include dizziness, sweating, and shakiness.

14. Does Mounjaro cause fatigue? Some people report tiredness, likely due to calorie reduction and metabolic adjustments.

15. Can Mounjaro cause pancreatitis? Yes, though rare. Seek medical help if you experience severe stomach pain that radiates to your back.

16. Is hair loss a side effect of Mounjaro? Hair loss is not a direct side effect, but rapid weight loss can trigger temporary shedding.

17. Does Mounjaro cause Ozempic face? Yes, significant weight loss can lead to facial volume loss, sometimes called "Ozempic face."

18. Can Mounjaro cause acid reflux? Some users experience acid reflux or heartburn, which can be managed with dietary changes or medications.

19. Does Mounjaro cause constipation? Yes, slowing digestion can lead to constipation. Increase fiber intake, stay hydrated, and consider a stool softener if needed.

20. Can Mounjaro cause depression or mood changes? Mood changes are not common but have been reported. Consult a doctor if you experience significant mood swings.

Weight Loss & Diet

21. How much weight can I lose on Mounjaro? Clinical trials show patients can lose 15-20% of their body weight over 72 weeks.

22. Do I need to follow a special diet on Mounjaro? A healthy, protein-rich diet supports weight loss and minimizes side effects. Avoid greasy, high-carb foods.

23. Can I drink alcohol while on Mounjaro? Alcohol can increase the risk of low blood sugar and worsen nausea. Drink in moderation and monitor your response.

24. Can I use Mounjaro if I have binge eating disorder? It may help reduce binge eating by suppressing appetite, but consult a specialist.

25. Does Mounjaro work if I don’t change my diet? It may still lead to weight loss, but healthy eating and exercise enhance results.

26. Will I regain weight after stopping Mounjaro? Likely, unless lifestyle changes are maintained. Weight regain occurs if appetite suppression is lost.

27. Does Mounjaro cause muscle loss? Rapid weight loss can include muscle loss. Prioritize protein intake and resistance training.

28. How long can I stay on Mounjaro? As long as it's effective and safe for you, under medical supervision.

29. Does Mounjaro reduce cravings? Many users report reduced cravings, especially for sugar and carbs.

30. Can I take appetite suppressants with Mounjaro? Combining them isn’t recommended without medical supervision due to potential risks.

Drug Interactions & Contraindications

31. Can I take Mounjaro with metformin? Yes, they are often prescribed together for better blood sugar control.

32. Can I use Mounjaro with insulin? Yes, but insulin doses may need adjustment to prevent low blood sugar.

33. Does Mounjaro interact with birth control? It can delay stomach emptying, potentially affecting oral contraceptive absorption. Consider an alternative method.

34. Can I take Mounjaro with thyroid medication? Yes, but take thyroid meds on an empty stomach, separate from Mounjaro.

35. Can Mounjaro be taken with other weight loss medications? Some doctors prescribe it with other meds like phentermine, but this should be closely monitored.

Special Populations

36. Can pregnant women take Mounjaro? No, it is not recommended during pregnancy.

37. Can breastfeeding women take Mounjaro? It is unknown if Mounjaro passes into breast milk, so it's not advised.

38. Can I take Mounjaro if I have kidney disease? Yes, but kidney function should be monitored.

39. Can people with a history of thyroid cancer take Mounjaro? No, it is not recommended for those with a history of medullary thyroid carcinoma.

40. Is Mounjaro safe for people with heart disease? It may have heart benefits, but consult a doctor if you have cardiovascular concerns.

Practical Questions

41. How do I store Mounjaro? Keep it in the fridge. If needed, it can be stored at room temperature (≤30°C) for up to 21 days.

42. How do I dispose of Mounjaro pens? Use an FDA-approved sharps container for safe disposal.

43. Is Mounjaro covered by insurance? Coverage varies. Some insurance plans cover it for diabetes but not for weight loss.

44. How much does Mounjaro cost? Without insurance, it can cost around $1,000 per month.

45. Is there a Mounjaro savings card? Yes, Eli Lilly offers savings programs for eligible patients.

46. Can I travel with Mounjaro? Yes, store it properly and carry a doctor's note if flying.

47. Can I inject Mounjaro in the same spot every time? Rotate injection sites to prevent irritation.

48. Does Mounjaro hurt when injected? Most people find it painless or mildly uncomfortable.

49. Does Mounjaro expire? Yes, check the expiration date before use.

50. Can I use Mounjaro if I don’t have diabetes? Off-label use for weight loss is becoming common but should be done under medical supervision.